CRP and bacterial infectious disease with sepsis: Using Δ CRP and Δ WCC levels in order to evaluate their respective evolution over time, multivariate analysis showed that Gram negative aetiology of bacteremia was independently associated with (i) an increase of CRP levels of 5 mg/dL, and (ii) an increase of WCC of 5,000 × 103 cells/mm3 from two days prior until one day after onset of bacteremia, respectively.