In multivariate analysis, controlling for type of ART intervention, a baseline CD4+ T-lymphocyte count <200 cells/mm3, IPT, and prior history of TB, hospitalization, incarceration and IDU (Table 5), only HAART (vs. ART naïve) was associated with a statistically significant reduction in TB disease incidence [HR 0.2 (95% CI 0.1, 0. Here, CD4 is linked to tuberculosis.