There are two recent reports of copy number variation (CNV) in the region that are relevant: CNV of the FCGR3B locus is associated with nephritis in a rat model and in human patients [36], and analysis of SNP genotypes and genomic hybridization with the HapMap sample has identified a 256 Kbp region as human copy number locus CNV_ID_62 containing the FCGR2A, HSPA6, FCGR3A, FCGR2B and FCRLM1 loci [37]. The gene discussed is FCRLA; the disease is nephritis.