The expression of many components of ECM including collagens, decorin, versican, fibromodulin, intergrins, extracellular matrix protein 1 (ECM-1), syndecan and ESM-1 has been identified in leiomyomas [11,17,26] as well as dermal wounds during healing, scars and keloids (for review see [27-32]). Here, ECM1 is linked to leiomyoma.