We validated the expression of ECM-2, ESM1, THBS1, FBLN5 and COL18A1 in keloids, incisional scars and adhesions and the analysis indicated an elevated expression of ECM2, THBS1 and FBLN5 in keloid/incisional scars and COL18 in peritoneal adhesions as compared to leiomyomas[17]. The gene discussed is ESM1; the disease is keloid.