ADAM17 and type 2 diabetes mellitus: ADAM gene expression in Type 2 diabetes LDL treated cells was significantly higher compared to control LDL treated cells for a] ADAM 28 after 4 and 24 hours at higher LDL concentrations b] ADAM17 after 4 hours at higher LDL concentrations c] ADAM 15 at 4 hours at higher LDL concentrations.