CD4 and HIV infectious disease: In multivariate analysis, low birth weight (<2,500 g) was the only factor associated with acquisition of HIV infection, with an adjusted hazard ratio of 5.63 (95% CI 1.62–19.49, p = 0.006), controlling for infant feeding practice, gender, maternal ARV drug regimen, WHO staging, absolute CD4 T count, haemoglobin level, and age at baseline.