When anxiety levels in the elevated plusmaze were assessed in a cohort of 6-month-old GFAP-apoE male mice,in which the expression of apoE3 or apoE4 is targeted toastrocytes, GFAP-apoE3, but not GFAP-apoE4, male mice showed lessmeasures of anxiety in the elevated plus maze thanApoe−/− mice (Table 2). This evidence concerns the gene APOE and Anxiety.