NR3C2 and Anxiety: These behaviors are linked to the limbic system and arepart of the behavioral repertoire tested in spatial memory tasksand also in fear conditioning [7].With respect to unconditioned fear-related behavior,Smythe et al. [8] have described that MRmodulates anxiety-like behavior of rats in the light/dark box.Oitzl et al. have shown that intracerebroventricular injection ofa rather selective MR antagonist in rats influencedcorticosterone-induced behavioral reactivity to spatial novelty [9].