PPARγ is expressed predominantly in white andbrown adipose tissue and is important in the regulation and control ofadipocyte development and function [18].Treatment with PPARγ agonists enhances the action of insulin and reduces serum glucose in subjects with T2DM, however, substantial body weight gain also occurs that is comprised of both fat mass and fluid volume [19–22]. Here, PPARG is linked to type 2 diabetes mellitus.