Similar results have been observed in other cell types.Differentiation of hepatic stellate cells to a myofibroblastphenotype is a key step in liver fibrosis [80–82].PPARγ agonists suppress proliferation of hepatic stellatecells and chemotaxis in response to platelet-derived growth factor(PDGF) [83], and induce hepatocyte growth factor (HGF), ananti-fibrotic cytokine [84]. The gene discussed is HGF; the disease is Hepatic fibrosis.