PPARG and atherosclerosis: PPARβ/δ is a more ubiquitously expressed isoform that stimulates fatty acid oxidation in heart and skeletal muscle [2] and whose diverse functions include cell differentiation [3] and participation in placental development, cancer [4],wound repair [5], and atherosclerosis [6].PPARγ, expressed in many tissues including adipose, vascular endothelium and smooth muscle, and heart among others, is an important regulator of genes involved in cellular differentiation, particularly adipogenesis, lipid metabolism, and glucosehomeostasis.