The network shows that RXRA interacts with proteins related to a tumor (THRA related to pituitary adenome) and those related to certain diseases caused by abnormalities in lipid metabolism (e.g., NR0B2 related to obesity, PPARA to hyperapobetalipoproteinemia, and PPARGC1A to lipodystrophy). Here, THRA is linked to obesity due to melanocortin 4 receptor deficiency.