Individuals with the XPC PAT(+/+)/XRCC3 241Met/Met or XPD 751Gln/Gln/XRCC3 241Met/Met genotypes showed a not significant higher risk of developing lung cancer 3.06 (CI = 0.91–10.30) (P = 0.071) and 2.66 (CI = 0.74–9.62) (P = 0.135) respectively. This evidence concerns the gene XPC and lung cancer.