Tri-colour FISH using the BAC probes spanning the band 10q23.2, 5′ flanking PTEN probe on the centromeric side of the locus, PTEN locus (10pq23.31), and more telomeric probes mapping to 10q23.33 and 10q25.1, was performed on 10 of the 107 adenocarcinomas with hemizygous PTEN deletion and three of the 107 adenocarcinomas with homozygous PTEN deletion (Table 5). The gene discussed is PTEN; the disease is adenocarcinoma.