Studies of families with breast and/or ovarian cancer who harbour disease-associated BRCA2 mutations have reported that male family members who carry such mutations have an increased RR of prostate cancer (BCLC, 1999; Johannsson et al, 1999; Eerola et al, 2001; Tulinius et al, 2002; Bermejo and Hemminki, 2004; van Asperen et al, 2005). Here, BRCA2 is linked to prostate carcinoma.