rFVIIa (NovoSeven®; Novo Nordisk A/S) is indicated for the treatment of bleeding episodes and for the prevention of bleeding during surgery or invasive procedures in patients with congenital hemophilia A and B with inhibitors to coagulation factors VIII (FVIII) or IX (FIX) or in those expected to have a high anamnestic response to FVIII or FIX, acquired hemophilia, congenital FVII deficiency, and in Europe for Glanzmann's thrombasthenia refractory to platelet transfusions. This evidence concerns the gene F8 and hemophilia.