rFVIIa (NovoSeven®; Novo Nordisk A/S) is indicated for the treatment of bleeding episodes and for the prevention of bleeding during surgery or invasive procedures in patients with congenital hemophilia A and B with inhibitors to coagulation factors VIII (FVIII) or IX (FIX) or in those expected to have a high anamnestic response to FVIII or FIX, acquired hemophilia, congenital FVII deficiency, and in Europe for Glanzmann's thrombasthenia refractory to platelet transfusions. This evidence concerns the gene F8 and Glanzmann thrombasthenia.