LG2 markers include 190 genes, among which are many oncogenes, (BCL2 (down, breast cancer poor prognosis marker), RAD51 (up), EGFR (up), RUNX3 (up), BCL9 (down) and VAV3 (down) and tumor suppressor gene NME1 (up). This evidence concerns the gene NME1 and breast carcinoma.