SELPLG and hepatocellular carcinoma: The t10, c12 CLA isomer has been shown to inhibit growth and induce apoptosis in a number of cell lines, such as HT-29 human colon cancer cells (Cho et al., 2005, 2006), Caco-2 colon cancer cells (Kim et al., 2002b), human colorectal cancer (CRC) cells (Lee et al., 2006), dRLh-84 rat hepatoma cells (Yamasaki et al., 2005) and the PC-3 human prostatic carcinoma cell line (Ochoa et al., 2004), while similar effects have not been reported for the c9, t11 CLA isomer at the same concentrations.