In our previous screening for mutations in the peripherin/RDS gene and in other RP and MD related genes in index cases of autosomal dominant retinopathies and simplex cases of RP, we found a lower contribution (1.3%) of mutations in peripherin/RDS to ADRP [13] in a Spanish population as compared to other screened populations. This evidence concerns the gene PRPH2 and retinitis pigmentosa 1.