FOXC1 and Rieger anomaly: Mutations in the FOXC1 gene can cause a wide variety of phenotypes that share features with Axenfeld anomaly, Rieger anomaly, ARS, iridogoniodysgenesis anomaly, iridogoniodysgenesis syndrome, iris hypoplasia, iridogoniodysgenesis type 1, anterior segment mesenchymal dysgenesis, and congenital glaucoma [2-13].