Incidentally, the top 15 feature genes that show the highest average ranks by t-statistics in the LOOCV test and that are considered to be associated with oral carcinoma metastasis are: HFE (AF150664), FLJ12529 (NM_024811), CXorf56 (NM_022101), HEATR1 (NM_018072), MGAM (NM_004668), APOL3 (NM_014349), PYY2 (NM_021093), RBP3 (J03912), UBE2V1 (NM_003349, NM_021988, NM_022442, NM_199144, NM_199203), KCNJ15 (U73191), GLS (AB020645), ARHGEF3 (NM_019555), MDM1 (NM_020128), ZC3H13 (AL136745), and C9orf16 (NM_024112). This evidence concerns the gene GLS and lip and oral cavity carcinoma.