TGFBR1 and Marfan syndrome: In adulthood, the other Ehlers-Danlos syndromes, as well as Marfan syndrome (OMIM #154700) and Loeys-Dietz syndrome (OMIM #609192) caused by mutations in the genes TGFR1 (OMIM #190181) or TGFR2 (OMIM #190182) [51,52], and arterial tortuosity syndrome (OMIM 208050) caused by a deficit in GLUT10 [53] can sometimes pose a problem.