Considering the screening of consecutively-collected unselected BC cases, the fraction of 1.4% BRCA2 mutation carriers is analogously low in breast cancer patients from North Sardinia (again, a quite sharp contrast between our frequencies and those observed in unselected cases from either Ashkenazi Jewish [23,24] and Icelandic [22,25] populations was observed). Here, BRCA2 is linked to breast carcinoma.