Particularly, a variable number of tandem repeats (VNTR) polymorphism, which is located 75 bp downstream the second polyadenylation signal at the 3' end of the Apo B gene (2p24-p23) has been found to be common in some ethnic groups [18-21], and it has been reported to be associated with modifications of lipid concentrations [22-28] and the risk of CHD [25-30] in some studies but not in others [31,32]. The gene discussed is APOB; the disease is coronary artery disorder.