Disorders of lipid metabolism such as elevated serum levels of total cholesterol (TC) [1-3], triglycerides (TG) [4,5], low-density lipoprotein cholesterol (LDL-C) [6,7], and apolipoprotein (Apo) B [8-11] have been considered important risk factors in the pathogenesis of atherosclerosis and CHD [12]. The gene discussed is APOB; the disease is atherosclerosis.