Filling of four questionnaires (background information, Psychosocial Adjustment to Illness Scale (PAIS), State-Trait Anxiety Inventory, Locus of control) by a mean of 13.34 months after surgery or 9.89 months after end of treatment. Medical parameters were also examined (stage of disease, estrogen/progesterone receptor status). The health state of patients was examined again 3 and 5 years after surgery. The gene discussed is PGR; the disease is Anxiety.