There was no correlation between EGFR FISH+ status and mutation of either EGFR exon 19 (p = 0.0543) or exon 20 (p = 0.283); female gender (p = 0.378); Asian ethnicity (p = 1.00); smoking status (p = 1.00); adenocarcinoma histology (p = 0.167); response to gefitinib (p = 0.552) or disease control (p = 0.653). This evidence concerns the gene EGFR and adenocarcinoma.