ERBB2 and adenocarcinoma: Likewise, HER2 FISH+ did not correlate with the presence of mutation of either EGFR exon 19 (p = 1.00) or exon 20 (p = 0.544); increased EGFR copy number (p = 1.00); gender (p = 0.593); Asian ethnicity (p = 0.593); smoking status (p = 1.00); adenocarcinoma histology (p = 0.408); response to gefitinib (p = 0.437) or disease control (p = 0.239).