Therefore, we used medulloblastoma cell lines to assay responses to genotoxic stress in the form of chemotherapeutic agents used to treat medulloblastoma clinically (cisplatin (CDDP), etoposide (VP-16)) and another agent, doxorubicin, previously studied for TP73 induction (Figure 5A). Here, TP73 is linked to medulloblastoma.