Differences have also been illustrated on differential expression of DAL-1 and NF2 between intracranial and spinal cord ependymomas [47], methylation of RASSF1A and TRAIL pathway-related genes in childhood intracranial ependymomas [48], and methylation of 9p21 tumor suppressor genes following clinico-histological parameters of ependymal tumors [7]. The gene discussed is TNFSF10; the disease is ependymal tumor.