Interestingly, SFRP1 was found also decreased in 30 (30%) of 100 HCC specimens as compared to adjacent non-cancerous livers (p < 0.05), where the stain intensity of SFRP1 in those non-cancerous livers was generally scored to the scale of 3+. The gene discussed is SFRP1; the disease is hepatocellular carcinoma.