Previous studies have established that testicular germ cell tumour cells can express both mRNA and protein of IFN-γ and the expressed IFN-γ is able to induce the chemokine IP-10, indicating its biological activity, whereas it is not able to phosphorylate the downstream STAT1 (Schweyer et al, 2002, 2003). The gene discussed is IFNG; the disease is germ cell tumor.