We next examined DC subpopulations in infected and naïve mice and observed that the following subsets were more prevalent in mice following infection with the nonlethal strain compared to the lethal strains: CD45R(B220)+ DCs (3-fold); CD8+ DCs (2.8-fold); CD4+ DCs (2.3-fold); and CD4−/CD8− DCs (2.5-fold). Here, CD4 is linked to infection.