We then enumerated the number of CD11c+ DCs per spleen following both infections and found that P. yoelii YM and P. yoelii 17XNL infections induced 3.5- and 10-fold increases, respectively, in the total numbers of CD11c+ DCs in the spleen compared to naïve mice (Figure 2C). The gene discussed is ITGAX; the disease is infection.