FMO5 and retinopathy of prematurity: To understand the role of oxidative compounds in ROP development we used the 50/10 OIR model and analyzed for lipid hydroperoxides (LHP), which are end-products of oxidative stress and themselves causative of IVNV [29], and for gp91phox, a subunit of NAD(P)H oxidase, which can increase the release of reactive oxygen species and trigger many signaling pathways including apoptotic and inflammatory pathways [30].