Cell transformation (Myc), mismatch repair (HMGB1, MSH2, MSH6, PCNA), arrest in mitosis (BIRC5, BUB1B, CDC2.CHEK1, CSE1L, MAD2L1, MIF, PLK1), migration/cytokinesis (ANLN, CDC42, FN1, ITGB5, MSF, SPARC, TOP2A), survival (AKT2, APEX1, BIRC5), gastric carcinoma progression (COL1A1, FUS), folate metabolism (MTHFD1, MTHFD2). The gene discussed is MAD2L1; the disease is gastric carcinoma.