From the 1,798 transcripts differentially expressed among the four mouse models of CRC, more than 70% (n = 1265) distinguished ApcMin/+ and AOM tumors versus Smad3-/- and Tgfb1-/-; Rag2-/- tumors (Figure 2a, bottom). This evidence concerns the gene TGFB1 and colorectal carcinoma.