Protein synthesis (Csf1, Eif5, Gadd45g, Itgb1, Sars, Tnf, Traf6), transformation (Ccnd1), formation of hepatoma cell line (Hras, Pin1, Shfm1), cell growth (Nrp1, Tnf), invasion of lymphoma cell line (Itgb1, Itgb2), proliferation of ovarian cancer cell lines (Fst, Hras, Itgfb5, Sod2, Sparc), fibroblast cell cycle progression (Ccnf, E2f5, Hras, Map4, Rhoa, Skil), survival of epiblast (Dag1, Itgb1), cell adhesion (Icam1, Itgb1, Itgb2, Lu, Rhoa, Tnf). The gene discussed is SPARC; the disease is ovarian cancer.