Cell movement/proliferation of endothelial cells (ADIPOQ, CXCL12, ENPP2, FGF13, HGF, HHEX, MYH11, PTN), formation of endothelial tube and blood vessel (ADAMTS1, ANGPTL1, CCL11, CXCL12, ENPP2, F13A1, HGF, MEF2C, MYH11, PTEN), cell movement of cancer cells (CXCL12, CD36, HGF, IGF1, L1CAM, SFRP1, PTN), tumorigenesis (AGTR1, CNN1, ENPP2, FGF7, HGF, IGF1, KIT, L1CAM), Hirschprung disease (EDNRB, L1CAM). The gene discussed is HHEX; the disease is cancer.