Cell invasion (CD14, CTSB, CTSL, ETS1, FN1, FSCN, FST, INHBA, ITGB2, LOX, MMP2, MMP9, MMP11, MMP12, MMP13, MYLK, OSM, PLAU, RECK, RGS4, RUNX2, S100A4, SPP1, SULF1, TIMP3), adhesion of tumor cells (ADAM12, ANXA1, CCL3, CCL4, FN1, ICAM1, IL6, ITGA4, ITGB2, PLAU, SELE, THBS1), metastasis of carcinoma cell lines (CCL2, DAPK1, S100A4, TWIST1, WISP1), tumor cell spreading (FN1, PLAU, SNAI2, THBS1, TNC), progression of gastric carcinoma (APOE, COL1A1, COL1A2). The gene discussed is SPP1; the disease is neoplasm.