Among the genetic thrombophilia markers, the heterozygous carrier rate for factor V Leiden was 12.5% as against 0% in controls (RR 4.57 95% CI 2.23–4.57 P < 0.05) while the frequency of EPCR and PAI 4G/4G homozygous state were 3.13% (RR 2.0; 95% CI 0.3–3.8 P NS) and 40.63 % (RR 3.2 ; 95% CI 1.8–5.1 P < 0.05), respectively. This evidence concerns the gene F5 and Rare hereditary thrombophilia.