The Endostatin immunostaining scores on the breast cancer tissue micro array showed no association with tumour size (Jonckheere Terpstra observed test statistic = 8265.5; p = 0.35), nodal status (Mann-Whitney U test; z = -0.33; p = 0.74), tumour grade (Jonckheere Terpstra observed test statistic = 10557.5; p = 0.23), vascular invasion (Mann-Whitney U test; z = -0.5; p = 0.62) and oestrogen receptor status (Mann-Whitney U test; z = -0.43; p = 0.66). This evidence concerns the gene COL18A1 and breast cancer.