Therefore, the hormone receptor and C-erb B2 status in our case of moderately differentiated adenocarcinoma is indicative of early tumor development, similar to that observed in correspondent neoplasms arisen in the eutopic endometrium where hormonal receptor positivity and C-erb B2 negativity are most often associated with low grade and early-stage tumors [20,21]. The gene discussed is NR4A1; the disease is adenocarcinoma.