Staining with an anti-p16INK4a antibody demonstrated scattered, weak immunoreactivity in recurrent nevus cells whereas a strong, diffuse nuclear and cytoplasmic immunoreactivity (Gray-Schopfer et al., 2006; Nilsson & Landberg, 2006) was observed in the residual dermal nests of melanocytes (Fig. 1A, last row). Here, CDKN2A is linked to nevus.