IL10 and Hepatitis: Immunopathology is controlled initially by the regulatory cytokine IL-10, as IL-10-deficient mice succumb to acute liver inflammation 8, while chronic granulomatous fibrosis can be suppressed by T cells transfected with the forkhead box transcription factor p3 (Foxp3) 9, which is functionally associated with Treg activity 10, 11.