LIMK1 and breast carcinoma: Biochemical and in vivo studies have indicated that LIMK1 is involved in promotion and maintenance of the invasive behavior in prostatic and breast cancer cells [3-5] and that when injected in nude mice, breast cancer cells overexpressing LIMK1 are capable of formation of osteolytic lesions in lower extremities and induction of tumor angiogenesis [4,5].