Abnormalities in expression of activation molecules such as TCR , ZAP70 and p56 lck protein expression using western blot in BC (Kurt et al, 1998) as well as impaired expression of interferon-γ (IFN-γ) in BC and lung cancer using enzyme-linked immunosorbent assay (Caras et al, 2004) have been described. This evidence concerns the gene ZAP70 and breast cancer.