More importantly, we further confirmed the association of RANTES -28 C/G with the severity of SARS by studying the Beijing Chinese cohort and found that Beijing Chinese patients with CG (OR = 4.27, 95%CI: 1.64–11.1) and GG (OR = 3.34, 95%CI: 0.37–30.7) genotype were more severe, as defined by admission to intensive care units or deaths due to SARS. The gene discussed is CCL5; the disease is severe acute respiratory syndrome.