We observed that the frequency ofcancer gene orthologues on the chicken Z is not significantly different fromthe frequency of cancer gene orthologues on the chicken autosome regionsthat share HSA 5 and HSA 9 with the Z. Nor is the frequency of cancer geneswithin the Z-homologous and Z-nonhomologous regions of HSA 5 and 9different. This evidence concerns the gene ALB and cancer.