In previous reports, the frequency of the Pro/Pro genotype of TP53 codon 72 was about 7% to 30% [13,15,17,18,23,43,44], although 39.1% of patients with signet ring cell gastric carcinomas and 37.7% of female patients with lung carcinomas had the Pro/Pro genotype in subgroup analyses [15,44]. Here, TP53 is linked to lung carcinoma.