PTGS2 and atherosclerosis: Moreover genes encoding for a variety of proteins that have been associated with atherosclerosis were up-regulated including phospholipase A2 (PLA2G4C), prostaglandin synthase 2 (PTGS2) also known as cyclooxygenase-2, thrombin receptor like-1 and the gene encoding for superoxide dismutase 2 (SOD2).