Similarly, there was a significant association between reduced p27Kip1, tumor size, tumor type (p = 0.047), positive lymph node, stromal invasion (p = 0.001&p = 0.024) and FIGO stage (p = 0.002); between p21waf overexpression and tumor size (p = 0.001) and vaginal involvement (p = 0.042). The gene discussed is CDKN1B; the disease is neoplasm.