An associated cardiomyopathy has not been reported in typical CCD due to mutations in the RYR1 gene; however, cardiomyopathies associated with mutations in the MYH7 [21] and the ACTA1 [22] genes may feature central cores on muscle biopsy but do not share the typical clinical features of CCD. The gene discussed is RYR1; the disease is cardiomyopathy.