RAB3A and Anxiety: Using Rab3a knockout (−/−) and Ebd (loss-of-function)Rab3a mutant mice, a recent study has shown that Rab3a −/− micedisplay reduced cued fear conditioning, while Ebd mutants showboth reduced anxiety and cued fear conditioning(Table 1), accompanied by altered hippocampal andcortical expression of Rab3a [69].