CD4 T cells from LckcreIL-4Rα−/lox mice induced 2.5-, 1.6-, and 2-fold more IFN-γ when compared with those from IL-4Rα−/− and WT or IL-4Rα−/lox mice at 10, 6, and 12 wk after infection (Figure 5C), respectively. Here, CD4 is linked to infection.