Culture supernatants from HFA 24 h after mock infection, infection with VSV-G pseudotyped NL4-3 that carries an incapacitating mutation in gp120 (VSV/NL4-3), and infection with native HIV-1/NL4-3 all contained IL-8, but the chemokine expression was increased by VSV/NL4-3 and native HIV-1 exposure. Here, CXCL8 is linked to infection.