Cellular adhesion molecules (CAMs), namelyintercellular adhesion molecule-1 (ICAM-1), and vascular celladhesion molecule-1 (VCAM-1), are poorly expressed by the restingendothelium, but are upregulated during inflammatory atherogenesisand may be an index of endothelial activation or even a molecularmarker of early atherosclerosis [4]. The gene discussed is ICAM1; the disease is atherosclerosis.